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Grants to USA Junior Investigators for Research Projects Related to the Aging Process


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Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty

Glenn Foundation for Medical Research (GFMR) and American Federation for Aging Research (AFAR)

Agency: Foundation

GrantWatch ID #199525

Grant Description

Grants to USA early-career investigators for research projects related to the aging process. Funding is intended to advance the careers of junior investigators in the field. Eligible research projects are those that examine the mechanisms of aging. Applicants from underrepresented groups in the biomedical sciences are strongly encouraged to apply.

The Glenn Foundation for Medical Research (GFMR) and AFAR provide funding to junior faculty (MDs and PhDs) to conduct research that will serve as the basis for longer term research efforts on the biology of aging. These investigators study a broad range of biomedical and clinical topics related to aging. 

The major goal of this program is to assist in the development of the careers of junior investigators committed to pursuing careers in the field of aging research. GFMR and AFAR support research projects concerned with understanding the basic mechanisms of aging rather than disease-specific research. Projects investigating age-related diseases are supported if approached from the point of view of how basic aging processes may lead to these outcomes. Projects concerning mechanisms underlying common geriatric functional disorders are also encouraged, as long as these include connections to fundamental problems in the biology of aging. Projects that deal strictly with clinical problems such as the diagnosis and treatment of disease, health outcomes, or the social context of aging are not eligible.

Examples of potentially fundable areas of research include, but are not limited to:

  • Aging and immune function
  • Stem cell aging
  • Inflammation
  • Genetic control of longevity
  • Neurobiology and neuropathology of aging
  • Invertebrate or vertebrate animal models
  • Cardiovascular aging
  • Aging and cellular stress response
  • Metabolic and endocrine changes

Four criteria are used to determine the merit of an application:

  • Qualifications and research record of the applicant;
  • Quality of the proposed research in the basic biology of aging;
  • Excellence of the research environment;
  • Likelihood that the project will advance the applicant's career in aging research.

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  • Others (see text field entitled "Additional Eligibility Criteria" for clarification)

Additional Eligibility Criteria:

The applicant must be an independent investigator with independent research space as described in a form completed by the Dean or Department Chair, and must be no more than 10 years beyond the start of postdoctoral research training as of July 1, 2023. For Awards funded by the GFMR preference will be given to investigators who are in the first 3 years of a faculty appointment. Exceptions to the ten year rule may be requested by emailing an NIH-style biosketch to AFAR at least one week prior to the deadline date.

The Glenn Foundation for Medical Research and AFAR Grants for Junior Faculty do not provide support for:
- Postdoctoral fellows in the laboratory of a senior investigator
- Investigators who have received major extramural funding for research in any area as a PI or Co-PI (not Co-I) - such as an NIH R01, DP2, DP5, R35 or equivalent grant - prior to and including the start date of this award (applicants may hold K or R21 funding, or NSF funding provided direct costs do not exceed $200,000 a year)
- Senior faculty, i.e. at the rank of Associate Professor level or higher
- Former Glenn and AFAR Grants for Junior Faculty recipients
- Applicants for the 2023 Glenn Foundation for Medical Research Discovery Award, the 2023 Sagol Network GerOmic Award for Junior Faculty or the 2023 Hevolution/AFAR New Investigator Awards in Aging Biology and Geroscience Research
- Applicants who are conducting research at a for-profit institution, or at an institution outside of the United States
- Alzheimer's Disease and/or related dementias research

Projects investigating mechanisms of, or putative therapies for, Alzheimer’s Disease and related dementias, are not eligible for this award and investigators should consider applying instead to the Small Research Grant Program for the Next Generation of Researchers in Alzheimer's Disease (R03).

Pre-Application Information:

The Letter of Intent must be submitted by December 15, 2022, at 5:00 p.m., EST.

- LOI deadline: December 15, 2022
- Results LOI review: Mid-March 2023
- Deadline full application: Late April 2023
- Award Announcement: Mid-June 2023
- Award Start Date: July 1, 2023

Things to Consider When Applying:


Additional Funding Information:

Number of Grants:

It is anticipated that approximately 8 grants will be awarded in 2023.

Estimated Size of Grant:

This Award has been increased from $125,000 to $150,000 for the 2023 award cycle.

Term of Contract:

Applicants may propose to use the award over the course of one or two years as justified by the proposed research. Funding will begin July 1, 2023.

Contact Information:

Upload letters of intent at

Institutional Commitment forms must be submitted via email to

AFAR grants department:

American Federation for Aging Research
55 West 39th Street, 16th Floor
New York, NY 10018
(212) 703-9977

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